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KMID : 0377619680140060487
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Korean Jungang Medical Journal
1968 Volume.14 No. 6 p.487 ~ p.491
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Effect of Penicillin and Methicillin on the Production of Lysozyme-Like Substances by Staphylococci
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崔朔德/Choi, Sak Duk
崔鉉浩/金永權/李在九/Choi, Hyon Ho/Kim, Young Kwon/Lee, Jae Koo
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Abstract
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The effect of penicillin (PC) and methicillin (MC) on the production of lysozyme-like substances by staphylococci was studied with the following results.
1. Staphylococci increase the production of lysozyme-like substances when they become resistant to MC, but the increase in the PC resistance does not effect the production of lysozyme-like substances.
2. Lysozyme-like substances produced by MC-sensitive staphylococci were stable in two day culture fluid, but those produced by MC-resistant strains disappear in two-day culture. The substances produced by PC-sensitive and resistant strains were stable both in one and two-day culture.
3. MC have a tendency to inhibit the production of lysozyme-like substances, but PC does not.
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KEYWORD
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